Grayanotoxin is known as andromedotoxin, acetylandromedol, rhodotoxin, and asebotoxin; it is a naturally produced from the Rhododendron species and Ericaceae family. Honey (Mad Honey) made from the pollen and nectar of these plants may contain a high level of grayanotoxins.
Consumption of this mad honey can cause a rare poisonous reaction called grayanotoxin poisoning, mad honey disease, honey intoxication, or rhododendron poisoning.
Despite the risk of cardiac problems, grayanotoxin poisoning is rarely fatal in humans. Thus, patients exposed to low doses of grayanotoxin typically recover within a few hours. Symptoms may last for 24 hours or longer if they consume a higher dosage.
The Rhododendron species with the highest concentration of grayanotoxins such as R. ponticum, R. flavum and R. luteum.
Mad honey can also be extracted from other grayanotoxin containing plants;
Andromeda polifolia, Spoonwood (Sheep-Laurel), and Lestrimelitta Limao contain high levels of grayanotoxin, capable of causing full-body paralysis and diaphragm paralysis.